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Macros are the three macronutrients — protein, carbs, and fat — expressed as a percentage of total calories. The classic balanced diet is 50% carbs, 30% protein, 20% fat. Low-carb/keto diets shift to 5-10% carbs, 25-30% protein, 60-70% fat. Protein at 1.6-2.2g per kg bodyweight maximizes muscle synthesis.